🧬 BioCosm
P1: Drug target extraction pipeline (ClinicalTrials.gov → drug_programs.json)
critical
Phase 1/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P1: Target database (data/targets.json — gene, UniProt ID, AlphaFold URL, disease assoc)
critical
Phase 1/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P1: OpenTargets integration — target validation scores
high
Phase 1/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P1: AlphaFold structure fetcher (UniProt → PDB/mmCIF cache)
high
Phase 1/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P1: Evidence score calculator (5-factor weighted composite)
critical
Phase 1/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P1: PostgreSQL schema design + initial data load
high
Phase 1/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P1: SEC EDGAR Form 4 pipeline — biotech insider filings
high
Phase 1/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P1: FDA PDUFA calendar scraper
high
Phase 1/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P1: Relationship mapper (same-target, same-company, dx↔tx cross-links)
high
Phase 1/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P1: Fix OpenInsider scraper HTML parsing
medium
Phase 1/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P3: Mol*/3Dmol.js integration — protein structure in side panel
high
Phase 3/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P3: Binding site highlighting on protein structures
medium
Phase 3/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P3: Structure caching + lazy loading system
medium
Phase 3/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P4: AI science summaries for each target (3-4 sentences, PhD level)
high
Phase 4/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P4: Nathan review/edit workflow for science content
medium
Phase 4/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P4: Competitor mapping per target (auto-generated from data)
high
Phase 4/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P4: Unmet need indicator per target (🔴🟡🟢)
medium
Phase 4/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P5: Insider signal overlay (green flares/rings on stars)
high
Phase 5/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P5: Catalyst countdown system (amber rings, days-until)
high
Phase 5/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P5: Daily digest overlay animation (what changed since yesterday)
medium
Phase 5/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P5: Phase transition detection pipeline
medium
Phase 5/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P6: Discovery Mode — guided 'planetarium show' tour
medium
Phase 6/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P6: Time Warp Mode — scrub through years of biotech evolution
medium
Phase 6/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P6: Sound design — subtle ambient interaction audio
low
Phase 6/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P6: Shareable snapshots (branded images for Twitter/X)
high
Phase 6/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P6: Nathan's Notes system ('N' badge on curated stars)
high
Phase 6/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P6: 'What If' simulator — toggle drug to approved, see ripple effects
low
Phase 6/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P7: Mobile responsive design (tap, bottom sheets, pinch-zoom)
high
Phase 7/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P7: Performance optimization (60fps with 50+ stars)
high
Phase 7/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P7: Deploy to Vercel/Railway + Supabase (production)
high
Phase 7/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P7: Stripe payment integration (free/paid/premium tiers)
high
Phase 7/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P7: Free/paid tier gating + auth system
high
Phase 7/7
📂 biocosm/biocosm-platform
🧬 BioCosm
AUTO: Daily cron — ClinicalTrials.gov refresh (6 AM)
medium
Phase post-launch
📂 biocosm/biocosm-platform
🧬 BioCosm
AUTO: Daily cron — SEC EDGAR Form 4 scrape (7 AM)
medium
Phase post-launch
📂 biocosm/biocosm-platform
🧬 BioCosm
AUTO: Daily cron — OpenInsider + prices + evidence recalc
medium
Phase post-launch
📂 biocosm/biocosm-platform
🧬 BioCosm
AUTO: Weekly cron — FDA calendar refresh (Monday 6 AM)
medium
Phase post-launch
📂 biocosm/biocosm-platform
📈 Alpha
Configure Alpaca trading integration
med
📂 alpha/alpaca-trading-setup
🔬 Research
GRAIL computational side projects
med
📂 research/grail-computational-opportunities
💼 Consulting
Nathan's consulting setup (CellSage LLC)
low
📂 consulting/nathan-consulting
💼 Consulting
Karilyn ISO 13485 / QMS business
med
Phase 1/5
📂 consulting/karilyn-iso-13485-business
🎮 AppDev
Nucleosome positioning game
med
Phase 1/4
📂 appdev/nucleosome-game
👨👩👧 Family
Karilyn postpartum fitness plan
med
📂 family/karilyn-postpartum-fitness
🤖 Gimli
Recursive self-evaluation loop
high
📂 gimli/recursive-self-evaluation
🤖 Gimli
Mission Control dashboard
high
📂 gimli/mission-control-dashboard
🤖 Gimli
Script-based heartbeat optimization
high
📂 gimli/script-based-heartbeat
🤖 Gimli
LanceDB vector memory search
high
📂 gimli/lancedb-vector-memory
🤖 Gimli
Gmail webhook monitoring
high
📂 gimli/gmail-webhook
🤖 Gimli
Command allowlist + sandbox mode
med
📂 gimli/command-allowlist
🤖 Gimli
Kimi K2.5 subagents
med
📂 gimli/kimi-k2-subagents
🤖 Gimli
ElevenLabs Agents voice calls
med
📂 gimli/elevenlabs-agents
🧬 BioCosm
P2A: Next.js project scaffold (App Router, TypeScript, Tailwind, design tokens)
critical
Phase 2A/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P2A: API routes — serve programs, targets, signals, relationships as JSON
critical
Phase 2A/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P2A: D3 force-directed constellation — layout engine + physics
critical
Phase 2A/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P2A: Star rendering — 8 visual dimensions (size, color, brightness, pulse, ring)
critical
Phase 2A/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P2A: Background — deep space gradient, faint star-chart grid (~5% opacity)
medium
Phase 2A/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P2A: Constellation lines — relationship edges between stars
high
Phase 2A/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P2B: Hover interaction — star grows, lines illuminate, unrelated dims
critical
Phase 2B/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P2B: Compact hover card (drug, company, target, phase dots, evidence, price, catalyst)
critical
Phase 2B/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P2B: Side panel deep dive — slides in from right on click
critical
Phase 2B/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P2B: Interactive legend + filter controls (left sidebar)
high
Phase 2B/7
📂 biocosm/biocosm-platform
🧬 BioCosm
P2B: Price sparkline chart in side panel (6mo, insider dates marked)
high
Phase 2B/7
📂 biocosm/biocosm-platform